Expression screening of cancer/testis genes in prostate cancer identifies nr6a1 as a novel marker of disease progression and aggressiveness
Identifieur interne : 000E81 ( Main/Exploration ); précédent : 000E80; suivant : 000E82Expression screening of cancer/testis genes in prostate cancer identifies nr6a1 as a novel marker of disease progression and aggressiveness
Auteurs : Romain Mathieu [France] ; Bertrand Evrard [France] ; Gaëlle Fromont [France] ; Nathalie Rioux-Leclercq [France] ; Julie Godet [France] ; Xavier Cathelineau [France] ; François Guillé [France] ; Michael Primig [France] ; Frédéric Chalmel [France]Source :
- The Prostate [ 0270-4137 ] ; 2013-07.
English descriptors
- KwdEn :
Abstract
Cancer/Testis (CT) genes are expressed in male gonads, repressed in most healthy somatic tissues and de‐repressed in various somatic malignancies including prostate cancers (PCa). Because of their specific expression signature and their associations with tumor aggressiveness and poor outcomes, CT genes are considered to be useful biomarkers and they are also targets for the development of new anti‐cancer immunotherapies. The aim of this study was to identify novel CT genes associated with hormone‐sensitive prostate cancer (HSPC), and castration‐resistant prostate cancer (CRPC).
Url:
DOI: 10.1002/pros.22659
Affiliations:
- France
- Nouvelle-Aquitaine, Poitou-Charentes, Région Bretagne, Île-de-France
- Paris, Poitiers, Rennes
- Université de Poitiers, Université de Rennes 1
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de Rennes 1</orgName></affiliation></author></analytic><monogr></monogr><series><title level="j">The Prostate</title><title level="j" type="abbrev">Prostate</title><idno type="ISSN">0270-4137</idno><idno type="eISSN">1097-0045</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2013-07">2013-07</date><biblScope unit="volume">73</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1103">1103</biblScope><biblScope unit="page" to="1114">1114</biblScope></imprint><idno type="ISSN">0270-4137</idno></series><idno type="istex">6636028DAD7073A903B1AA8F93CFB8DD8ED432B5</idno><idno type="DOI">10.1002/pros.22659</idno><idno type="ArticleID">PROS22659</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0270-4137</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cancer/Testis genes</term><term>NR6A1</term><term>biomarker</term><term>castration‐resistant prostate cancer</term><term>nuclear receptor</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">Cancer/Testis (CT) genes are expressed in male gonads, repressed in most healthy somatic tissues and de‐repressed in various somatic malignancies including prostate cancers (PCa). Because of their specific expression signature and their associations with tumor aggressiveness and poor outcomes, CT genes are considered to be useful biomarkers and they are also targets for the development of new anti‐cancer immunotherapies. The aim of this study was to identify novel CT genes associated with hormone‐sensitive prostate cancer (HSPC), and castration‐resistant prostate cancer (CRPC).</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Nouvelle-Aquitaine</li><li>Poitou-Charentes</li><li>Région Bretagne</li><li>Île-de-France</li></region><settlement><li>Paris</li><li>Poitiers</li><li>Rennes</li></settlement><orgName><li>Université de Poitiers</li><li>Université de Rennes 1</li></orgName></list><tree><country name="France"><region name="Région Bretagne"><name sortKey="Mathieu, Romain" sort="Mathieu, Romain" uniqKey="Mathieu R" first="Romain" last="Mathieu">Romain Mathieu</name></region><name sortKey="Cathelineau, Xavier" sort="Cathelineau, Xavier" uniqKey="Cathelineau X" first="Xavier" last="Cathelineau">Xavier Cathelineau</name><name sortKey="Chalmel, Frederic" sort="Chalmel, Frederic" uniqKey="Chalmel F" first="Frédéric" last="Chalmel">Frédéric Chalmel</name><name sortKey="Chalmel, Frederic" sort="Chalmel, Frederic" uniqKey="Chalmel F" first="Frédéric" last="Chalmel">Frédéric Chalmel</name><name sortKey="Evrard, Bertrand" sort="Evrard, Bertrand" uniqKey="Evrard B" first="Bertrand" last="Evrard">Bertrand Evrard</name><name sortKey="Fromont, Gaelle" sort="Fromont, Gaelle" uniqKey="Fromont G" first="Gaëlle" last="Fromont">Gaëlle Fromont</name><name sortKey="Fromont, Gaelle" sort="Fromont, Gaelle" uniqKey="Fromont G" first="Gaëlle" last="Fromont">Gaëlle Fromont</name><name sortKey="Godet, Julie" sort="Godet, Julie" uniqKey="Godet J" first="Julie" last="Godet">Julie Godet</name><name sortKey="Guille, Francois" sort="Guille, Francois" uniqKey="Guille F" first="François" last="Guillé">François Guillé</name><name sortKey="Guille, Francois" sort="Guille, Francois" uniqKey="Guille F" first="François" last="Guillé">François Guillé</name><name sortKey="Mathieu, Romain" sort="Mathieu, Romain" uniqKey="Mathieu R" first="Romain" last="Mathieu">Romain Mathieu</name><name sortKey="Primig, Michael" sort="Primig, Michael" uniqKey="Primig M" first="Michael" last="Primig">Michael Primig</name><name sortKey="Rioux Eclercq, Nathalie" sort="Rioux Eclercq, Nathalie" uniqKey="Rioux Eclercq N" first="Nathalie" last="Rioux-Leclercq">Nathalie Rioux-Leclercq</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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